For Research Use Only. Not for use in diagnostic procedures.
Comprehensive genetic analysis by targeted sequencing identifies risk factors and predicts patient outcome in Mantle Cell Lymphoma: results from the EU-MCL network trials
The authors demonstrate that applying the EuroClonality-NDC assay to DNA samples from peripheral blood and bone marrow reliably detects diagnostically and prognostically important genetic factors in MCL patients, facilitating genetic characterization in clinical routine.
Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma
Describes the molecular relationship between BCP-ALL and BCP-LBL using whole exome sequencing / transcriptomics. EuroClonality-NDC was used for IG/TR rearrangement analysis.
Large cell lymphoma through a liquid lens
Commentary/Editorial on the liquid biopsy manuscript below.
Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease
Describes the application of EuroClonality-NDC for cfDNA analysis in DLBCL during treatment and its association with clinical outcomes.
Development of a fully automated workflow for integrated genomic profiling of haematological malignancies
Shows the robustness of a fully automated protocol for the analysis of EuroClonality-NDC and Myeloid-NDC assays.
A novel next-generation sequencing capture-based strategy to report somatic hypermutation status using genomic regions downstream to immunoglobulin rearrangements
Describes a novel method to detect somatic hypermutation in IGH using the EuroClonality-NDC assay.
Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis
Describes the natural history of CLL using multiple technologies, including the EuroClonality-NDC assay.
Genotyping and Minimal Residual Disease (MRD) Assessment in cfDNA By the Euroclonality-NGS DNA Capture (EC-NDC) Panel in Mantle Cell Lymphoma (MCL)
Application of EuroClonality-NDC for cfDNA genotyping and MRD analysis in MCL.
Immunoglobulin/T Cell Receptor Capture Strategy for Comprehensive Immunogenetics
A more technical description of the EuroClonality-NGS DNA Capture (EuroClonality-NDC) assay, with step-by-step instructions and tips.
Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders
This is the main manuscript by the EuroClonality-NGS Working Group describing the validation and performance of the EuroClonality-NDC.