Publications

Development of a fully automated workflow for integrated genomic profiling of haematological malignancies

Shows the robustness of a fully automated protocol for the analysis of EuroClonality-NDC and Myeloid-NDC assays.

Scientific Paper

Publication date: 2024

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma

Describes the molecular relationship between BCP-ALL and BCP-LBL using whole exome sequencing / transcriptomics. EuroClonality-NDC was used for IG/TR rearrangement analysis.

Commentary/Editorial

Publication date: 2024

Large cell lymphoma through a liquid lens

Commentary/Editorial on the liquid biopsy manuscript below

Scientific Paper

Publication date: 2024

Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease

Describes the application of EuroClonality-NDC for cfDNA analysis in DLBCL during treatment and its association with clinical outcomes.

Scientific Paper

Publication date: 2023

Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis

Describes the natural history of CLL using multiple technologies, including the EuroClonality-NDC assay.

Scientific Paper

Publication date: 2022

A novel next-generation sequencing capture-based strategy to report somatic hypermutation status using genomic regions downstream to immunoglobulin rearrangements

Describes a novel method to detect somatic hypermutation in IGH using the EuroClonality-NDC assay.

Conference Abstract

Publication date: 2022

Genotyping and Minimal Residual Disease (MRD) Assessment in cfDNA By the Euroclonality-NGS DNA Capture (EC-NDC) Panel in Mantle Cell Lymphoma (MCL)

Application of EuroClonality-NDC for cfDNA genotyping and MRD analysis in MCL.

Scientific Paper

Publication date: 2022

Immunoglobulin/T Cell Receptor Capture Strategy for Comprehensive Immunogenetics

A more technical description of the EuroClonality-NGS DNA Capture (EuroClonality-NDC) assay, with step-by-step instructions and tips.

Scientific Paper

Publication date: 2021

Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders

This is the main manuscript by the EuroClonality-NGS Working Group describing the validation and performance of the EuroClonality-NDC

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Publications

Development of a fully automated workflow for integrated genomic profiling of haematological malignancies

Mutational and transcriptional landscape of pediatric B-cell precursor lymphoblastic lymphoma

Large cell lymphoma through a liquid lens

Liquid biopsy for molecular characterization of diffuse large B-cell lymphoma and early assessment of minimal residual disease

Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis

A novel next-generation sequencing capture-based strategy to report somatic hypermutation status using genomic regions downstream to immunoglobulin rearrangements

Genotyping and Minimal Residual Disease (MRD) Assessment in cfDNA By the Euroclonality-NGS DNA Capture (EC-NDC) Panel in Mantle Cell Lymphoma (MCL)

Immunoglobulin/T Cell Receptor Capture Strategy for Comprehensive Immunogenetics

Validation of the EuroClonality-NGS DNA capture panel as an integrated genomic tool for lymphoproliferative disorders

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